Abstract
This study explores the socio-economic factors that influence the implementation of One Health (OH) approaches in low-resource settings. OH is a collaborative, multisectoral, and transdisciplinary approach aimed at achieving optimal health outcomes by recognizing the interconnection between people, animals, plants, and their shared environment. Despite its potential, the adoption and sustainability of OH practices face significant challenges in resource-limited contexts. Through a qualitative and quantitative analysis of existing literature and case studies, this paper identifies key socio-economic barriers and facilitators, including financial constraints, community engagement, and policy support. The findings highlight the need for tailored strategies that address local socio-economic conditions to enhance OH implementation. This research contributes to the development of more effective and sustainable OH programs in low-resource settings, ultimately improving health outcomes for both humans and animals.