Regenerative Corrosion Index of Beta Phase Titanium Copper Alloy for Intrauterine Gynaecological Application

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Regenerative Corrosion Index of Beta Phase Titanium Copper Alloy for Intrauterine Gynaecological Application

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  • August 14, 2022
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The investigation of corrosion regenerative index on performance reliability of Intrauterine contraceptive beta phase Titanium Copper Alloy for gynecological application within the endometrium environment is investigated in comparative analysis with existing mono-element copper prototype, the Cu-T380(IUD).The existing Cu-T380(IUD) is associated with induced biocorrosion problems of fragmentation micro-structural load deformation – failure mode which cause expulsion phenomenon, biocompatibility – cell cytotoxicity phenomenon, microbial pathogenic skin rash reactions, Pelvic Inflammatory Disorders(PID), with copper allergenic cramp resulting in infection phenomenon. These adverse phenomenal effects of expulsion, biocompatibility and subsequent infection associated with copper Intrauterine Device necessitated the development of an optimally improved beta phase biomaterial alloy, Titanium Copper alloy (TiCu alloy). This research innovated the design and production of Beta((β) phase TiCu alloy in the categories of specimens; Ti0.5%Cu, Ti1.0%Cu, Ti2.0%Cu, Ti5.0%Cu, Ti10.0.0%Cu, Ti15.0%Cu and Ti17.0% Cu, using Copper element as the experimental control reference biomaterial. The TiCu alloy specimens were produced by powder metallurgy technique in an inert environment. Experimental investigations and Minitab Software Design analyses of corrosion resistance was carried out by Electrochemical Impedance Spectroscopy (EIS) using Hanks and Ringers solutions (Simulated Body Fluids) at body temperature of about 37c. The corrosion potential of the samples showed that Ti 17%Cu have value of -0.304 and -0.303 While copper indicated a corrosion potential of -0.242 and -0.243 for Hanks and Ringers solutions respectively. The Corrosion rate showed that Ti17%Cu sample has corrosion rate of 1.4mg/cm2yr and 1.6mg/cm2yr in the Hanks and Ringers solution respectively in comparison with 6.9mg/cm2yr and 7.0mg/cm2yr observed for the Copper specimen. The findings established Ti17%Cu alloy as a possible replacement to the existing prototype biomaterial (Cu-T380 (IUD).

Keywords: Regenerative Corrosion Index; Beta Phase Titanium Copper Alloy; Intrauterine Gynaecological Application

Authorship: Udeh O.U., Nwogbu C.C. and Nwogbu P.I. | FULL PDF

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