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Impact of Monosodium Glutamate (MSG) and Soya Bean Administration on Cancer Marker Levels in Rats: A Comparative Study

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Impact of Monosodium Glutamate (MSG) and Soya Bean Administration on Cancer Marker Levels in Rats: A Comparative Study

Adaeze Bob Chile-Agada PhD
Department of Biochemistry, Imo State University Owerri, Nigeria

Abstract
This study investigates the impact of monosodium glutamate (MSG) and soya bean consumption on cancer markers in rats, employing a rigorous methodology involving various laboratory equipment and chemicals. A comprehensive analysis of cancer markers was conducted using state-of-the-art instrumentation. The determination of pancreatic cancer markers (CA 19-9) involved employing a CA 19-9 ELISA kit. Serum samples were processed according to the manufacturer’s instructions. Relative Light Units for each sample were measured, and CA 19-9 concentrations were calculated in ng/ml. Colorectal cancer markers (CEA) were assessed using a CEA ELISA kit. Serum samples were processed similarly, and CEA concentrations were expressed in ng/ml. Additionally, ovarian cancer markers (CA-125) were examined using a CA-125 ELISA kit, with concentrations estimated in ng/ml. Statistical analyses were performed using one-way ANOVA, and data were reported as Mean ± Standard Deviation (S.D). The study utilized Statistical Package for Social Sciences (SPSS) version 20, with a confidence interval of 95% (p < 0.05). The findings elucidate significant alterations in cancer markers due to MSG and soya bean consumption, providing valuable insights into the potential health risks associated with these dietary components. This study contributes valuable data to the field, emphasizing the importance of understanding the intricate relationship between dietary elements and cancer markers, thereby paving the way for informed dietary choices and targeted preventive strategies.

Keywords ­­­­­­Cancer Markers; Monosodium Glutamate (MSG); Soya Bean Consumption; ELISA Analysis

Citation Bob Chile-Agada, A. (2022). Impact of Monosodium Glutamate (MSG) and Soya Bean Administration on Cancer Marker Levels in Rats: A Comparative Study. Global Journal of Biology and Life Sciences, 4(2) 1-10 https://doi.org/10.5281/zenodo.10369203  
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