Antibacterial – Microbial Performance of Beta Phase Titanium Copper Alloy for Intrauterine Gynaecological Application

• Post by: airjournal
• August 14, 2022
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The research study on the anti-bacterial property of beta phase TiCu alloy was handled by antibacterial test on Escherichia Coli (E.C) and Staphylococcus Aureus (S.A) colonies on the specimens. Research studies indicated that the Ti 17%Cu alloy specimen exhibited excellent antibacterial property, providing a great potential in clinical application for gynecological implants. The research of antimicrobial/antibiofilm activities of the beta phase contraceptive Titanium Copper alloy (TiCu) against these bacterial species showed an excellent antibacterial effect in vitro, thus inhibiting both Escherichia coli and Staphylococcus Aureus. This research innovated the design and production of Beta(β) phase TiCu alloy specimens in the categories of; Ti0.5%Cu, Ti1.0%Cu, Ti2.0%Cu, Ti5.0%Cu, Ti10.0.0%Cu, Ti15.0%Cu and Ti17.0% Cu, using Copper element as the experimental control reference biomaterial. The TiCu alloy specimens were produced by powder metallurgy technique in an inert environment. Experimental investigations and Minitab Software Design analyses on the specimens for combined antibacterial response in direct improvement of mechanical compatibility (tensile strength, hardness value, fracture toughness), biocompatibility–cell viability (cytocompatibility), was carried out in order to establish the suitability of Ti17%Cu alloy as a possible replacement to the existing prototype biomaterial (Cu-T380(IUD).

Keywords: Antibacterial; Microbial Performance; Beta Phase Titanium Copper Alloy; Intrauterine Gynaecological Application

Authorship: Udeh O.U., Nwogbu C.C., and Nwogbu P.I | FULL PDF